K6PC-5 ACTIVATES SPHK1-NRF2 SIGNALING TO PROTECT NEURONAL CELLS FROM OXYGEN GLUCOSE DEPRIVATION/RE-OXYGENATION

K6PC-5 Activates SphK1-Nrf2 Signaling to Protect Neuronal Cells from Oxygen Glucose Deprivation/Re-Oxygenation

Background/Aims: New strategies pomyslnaszycie.com are required to combat neuronal ischemia-reperfusion injuries.K6PC-5 is a novel sphingosine kinase 1 (SphK1) activator whose potential activity in neuronal cells has not yet been tested.Methods: Cell survival and necrosis were assessed with a Cell Counting Kit-8 assay and lactate dehydrogenase rele

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A Deadlock Prevention Policy for Flexible Manufacturing Systems Modeled With Petri Nets Using Structural Analysis

This paper derives an iterative deadlock prevention policy for systems of simple sequential processes with resources (S3PRs) based on structural analysis, which consists of two stages.The first stage is called siphons control.Strict minimal siphons (SMSs) in an S3PR net are computed and control places are added by imposing P-invariants associated w

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Family maintenance in private international law: Choosing between the UN Convention (1956) and the Hague Convention (2007)

Globalization and increased movement of people are a challenge for Private International Law.A proper legal regulation of cross-border dispute cases requires a higher degree of international cooperation.In the context of maintenance, it has generated the partnership of two world organizations, the Hague Conference on Private International Law and t

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Sustainability Strategy in Transforming Revolving Fund Management: Case Study of the Ex-National Program for Independent Community Empowerment Rural in Tuban Regency

Abstract After the conclusion of the National Program for Community Empowerment in 2015, Tuban Regency took the initiative to establish Regent Regulation Number 27 of 2018 to manage the remaining assets, including revolving funds.This research aims to describe and analyze the sustainability strategies for managing the revolving funds from the Natio

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